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 | Acesso ao texto completo restrito à biblioteca da Biblioteca Rui Tendinha. Para informações adicionais entre em contato com biblioteca@incaper.es.gov.br. |
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Registro Completo |
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Biblioteca(s): |
Biblioteca Rui Tendinha. |
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Data corrente: |
29/12/2014 |
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Data da última atualização: |
01/09/2015 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
BRASIL, G. A.; RONCHI, S. N.; NASCIMENTO, A. M.; LIMA, E. M. de.; ROMÃO, W.; COSTA, H. B. da.; SCHERER, R.; VENTURA, J. A.; LENZ, D.; BISSOLI, N. S.; ENDRINGER, D. C.; ANDRADE, T. U. de. |
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Afiliação: |
Girlandia Alexandre Brasil; Silas Nascimento Ronchi; Andrews Marques do Nascimento; Ewelyne Miranda de Lima; Wanderson Romão; Helber Barcellos da Costa; Rodrigo Scherer; Jose Aires Ventura, Incaper; Dominik Lenz; Nazaré Souza Bissoli; Denise Coutinho Endringer; Tadeu Uggere de Andrade. |
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Título: |
Antihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex. |
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Ano de publicação: |
2014 |
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Fonte/Imprenta: |
American Journal of Plant Sciences, 5, 2148-2153. 2014. |
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Descrição Física: |
Planta Med. 2014 Nov ;80(17):1580-7. |
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DOI: |
10.1055/s-0034-1383122 |
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Idioma: |
Inglês |
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Conteúdo: |
The aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension. MenosThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects eli... Mostrar Tudo |
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Palavras-Chave: |
Carica papaya; Mamão; Rubi INCAPER 511. |
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Thesaurus NAL: |
Antihypertensive; Hypertension. |
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Categoria do assunto: |
Q Segurança Alimentar |
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Marc: |
LEADER 03032naa a2200337 a 4500
001 1004730
005 2015-09-01
008 2014 bl uuuu u00u1 u #d
024 7 $a10.1055/s-0034-1383122$2DOI
100 1 $aBRASIL, G. A.
245 $aAntihypertensive Effect of Carica papaya Via a Reduction in ACE Activity and Improved Baroreflex.$h[electronic resource]
260 $c2014
300 $cPlanta Med. 2014 Nov ;80(17):1580-7.
520 $aThe aims of this study were to evaluate the antihypertensive effects of the standardised methanolic extract of Carica papaya, its angiotensin converting enzyme inhibitory effects in vivo, its effect on the baroreflex and serum angiotensin converting enzyme activity, and its chemical composition. The chemical composition of the methanolic extract of C. papaya was evaluated by liquid chromatography-mass/mass and mass/mass spectrometry. The angiotensin converting enzyme inhibitory effect was evaluated in vivo by Ang I administration. The antihypertensive assay was performed in spontaneously hypertensive rats and Wistar rats that were treated with enalapril (10 mg/kg), the methanolic extract of C. papaya (100 mg/kg; twice a day), or vehicle for 30 days. The baroreflex was evaluated through the use of sodium nitroprusside and phenylephrine. Angiotensin converting enzyme activity was measured by ELISA, and cardiac hypertrophy was evaluated by morphometric analysis. The methanolic extract of C. papaya was standardised in ferulic acid (203.41 ± 0.02 µg/g), caffeic acid (172.60 ± 0.02 µg/g), gallic acid (145.70 ± 0.02 µg/g), and quercetin (47.11 ± 0.03 µg/g). The flavonoids quercetin, rutin, nicotiflorin, clitorin, and manghaslin were identified in a fraction of the extract. The methanolic extract of C. papaya elicited angiotensin converting enzyme inhibitory activity. The antihypertensive effects elicited by the methanolic extract of C. papaya were similar to those of enalapril, and the baroreflex sensitivity was normalised in treated spontaneously hypertensive rats. Plasma angiotensin converting enzyme activity and cardiac hypertrophy were also reduced to levels comparable to the enalapril-treated group. These results may be associated with the chemical composition of the methanolic extract of C. papaya, and are the first step into the development of a new phytotherapic product which could be used in the treatment of hypertension.
650 $aAntihypertensive
650 $aHypertension
653 $aCarica papaya
653 $aMamão
653 $aRubi INCAPER 511
700 1 $aRONCHI, S. N.
700 1 $aNASCIMENTO, A. M.
700 1 $aLIMA, E. M. de.
700 1 $aROMÃO, W.
700 1 $aCOSTA, H. B. da.
700 1 $aSCHERER, R.
700 1 $aVENTURA, J. A.
700 1 $aLENZ, D.
700 1 $aBISSOLI, N. S.
700 1 $aENDRINGER, D. C.
700 1 $aANDRADE, T. U. de.
773 $tAmerican Journal of Plant Sciences, 5, 2148-2153. 2014.
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Registro original: |
Biblioteca Rui Tendinha (BRT) |
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Biblioteca |
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Origem |
Tipo/Formato |
Classificação |
Cutter |
Registro |
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Status |
Fechar
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Registro Completo |
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Biblioteca(s): |
Biblioteca Rui Tendinha. |
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Data corrente: |
19/08/2022 |
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Data da última atualização: |
19/08/2022 |
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Tipo da produção científica: |
Artigo em Periódico Indexado |
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Autoria: |
FILETE, C. A.; MOREIRA, T. R.; SANTOS, A. R. dos; GOMES, W. dos S.; GUARÇONI, R. G.; MORELI, A. P.; AUGUSTO, M. I.; ABREU, R. de O.; SIMMER, M. B.; CALIMAN, A. D. C.; GUIMARÃES, C. V.; BERELLI, S. da S.; FERRÃO, M. A. G.; FONSECA, A. F. A. da.; PARTELLI, F. L.; BERILLI, A. P. C. G.; OLIVEIRA, E. C. da S.; PEREIRA, L. L. |
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Afiliação: |
Cristhiane Altoé Filete, IFES Venda Nova do Imigrante; Taís Rizzo Moreira, UFES; Alexandre Rosa dos Santos, UFES; Willian dos Santos Gomes, UFES; Rogerio Carvalho Guarçoni, Incaper; Aldemar Polonini Moreli, Ifes Venda Nova do Imigrante; Maria Imaculada Augusto, IFES Venda Nova do Imigrante; Raabe de Oliveira Abreu, IFES Venda Nova do Imigrante; Marinalva Maria Bratz Simmer, IFES Venda Nova do Imigrante; Alice Dela Costa Caliman, IFES Venda Nova do Imigrante; Cleidiana Vieira Guimarães, IFES Venda Nova do Imigrante; Savio da Silva Berilli, UFES; Maria Amélia Gava Ferrão, Incaper/Embrapa Café; Aymbiré Francisco Almeida da Fonseca, Incaper/Embrapa Café; Fábio Luiz Partelli, UFES; Ana Paula Candido Gabriel Berilli, UFES; Emanuele Catarina da Silva Oliveira, IFES Venda Nova do Imigrante; Lucas Louzada Pereira, IFES Venda Nova do Imigrante. |
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Título: |
The New Standpoints for the Terroir of Coffea canephora from Southwestern Brazil: Edaphic and Sensorial Perspective. |
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Ano de publicação: |
2022 |
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Fonte/Imprenta: |
Agronomy, v. 12, n. 8, p. 1-17, 2022. |
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DOI: |
https://doi.org/10.3390/agronomy12081931 |
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Idioma: |
Inglês |
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Conteúdo: |
The sensory profile from the Coffea canephora stands out for being denser, less sweet, presenting less acidity, and having characteristics of a marked aroma of roasted cereals. Coffee is essentially a terroir product, that is, directly influenced by environmental aspects, both natural and anthropic, in this sense, it has been argued that Coffea canephora is linked to the context of inferior coffees in sensory terms by the terroir conditions. This study aimed to characterize and investigate the terroir in different areas of Conilon coffee production, with the application of different fermentation methods, and to observe their possible gains and losses in the sensory quality of Coffea canephora. Cherry coffee samples were collected in six municipalities in the state of Espírito Santo, Brazil, which has an altitude variation from 376 m to 866 m. The study showed that the local characteristics of altitude and temperature directly influence the sensory quality, as well as demonstrated that natural fermentation in a specific altitude zone delivered good results, fixing the terroir factor. Finally, it was demonstrated that induced fermentation helps to improve sensory quality for higher altitude areas, indicating the possibility of reformulating the terroir of Conilon coffee production. |
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Palavras-Chave: |
Café conilon; Edaphoclimatic factors. |
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Thesagro: |
Café; Cafeicultura; Coffea Canephora; Fermentação; Temperatura. |
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Thesaurus NAL: |
Coffea; Fermentation. |
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Categoria do assunto: |
-- |
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URL: |
https://biblioteca.incaper.es.gov.br/digital/bitstream/item/4212/1/The-NewStandpoints-Coffea-canephora-guarconi.pdf
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Marc: |
LEADER 02592naa a2200445 a 4500
001 1024205
005 2022-08-19
008 2022 bl uuuu u00u1 u #d
024 7 $ahttps://doi.org/10.3390/agronomy12081931$2DOI
100 1 $aFILETE, C. A.
245 $aThe New Standpoints for the Terroir of Coffea canephora from Southwestern Brazil$bEdaphic and Sensorial Perspective.$h[electronic resource]
260 $c2022
520 $aThe sensory profile from the Coffea canephora stands out for being denser, less sweet, presenting less acidity, and having characteristics of a marked aroma of roasted cereals. Coffee is essentially a terroir product, that is, directly influenced by environmental aspects, both natural and anthropic, in this sense, it has been argued that Coffea canephora is linked to the context of inferior coffees in sensory terms by the terroir conditions. This study aimed to characterize and investigate the terroir in different areas of Conilon coffee production, with the application of different fermentation methods, and to observe their possible gains and losses in the sensory quality of Coffea canephora. Cherry coffee samples were collected in six municipalities in the state of Espírito Santo, Brazil, which has an altitude variation from 376 m to 866 m. The study showed that the local characteristics of altitude and temperature directly influence the sensory quality, as well as demonstrated that natural fermentation in a specific altitude zone delivered good results, fixing the terroir factor. Finally, it was demonstrated that induced fermentation helps to improve sensory quality for higher altitude areas, indicating the possibility of reformulating the terroir of Conilon coffee production.
650 $aCoffea
650 $aFermentation
650 $aCafé
650 $aCafeicultura
650 $aCoffea Canephora
650 $aFermentação
650 $aTemperatura
653 $aCafé conilon
653 $aEdaphoclimatic factors
700 1 $aMOREIRA, T. R.
700 1 $aSANTOS, A. R. dos
700 1 $aGOMES, W. dos S.
700 1 $aGUARÇONI, R. G.
700 1 $aMORELI, A. P.
700 1 $aAUGUSTO, M. I.
700 1 $aABREU, R. de O.
700 1 $aSIMMER, M. B.
700 1 $aCALIMAN, A. D. C.
700 1 $aGUIMARÃES, C. V.
700 1 $aBERELLI, S. da S.
700 1 $aFERRÃO, M. A. G.
700 1 $aFONSECA, A. F. A. da.
700 1 $aPARTELLI, F. L.
700 1 $aBERILLI, A. P. C. G.
700 1 $aOLIVEIRA, E. C. da S.
700 1 $aPEREIRA, L. L.
773 $tAgronomy$gv. 12, n. 8, p. 1-17, 2022.
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Biblioteca Rui Tendinha (BRT) |
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