02434naa a2200277 a 450000100080000000500110000800800410001902400550006010000230011524502030013826000090034152015160035065300110186665300130187765300340189070000200192470000230194470000170196770000200198470000200200470000160202470000190204070000220205970000180208177300570209910221232020-02-18 2020 bl uuuu u00u1 u #d7 ahttps://doi.org/10.1016/j.indcrop.2019.05.0792DOI1 aGOMES, R. B. de A. aResidues from the Brazilian pepper tree (Schinus terebinthifolia Raddi) processing industrybChemical profile and antimicrobial activity of extracts against hospital bacteria.h[electronic resource] c2020 aSchinus terebinthifolia Raddi is a plant used in folk medicine in the treatment of various diseases and has several biological potentials. Its fruit is used as condiment and has high demand in the spice market. In the present study extracts of different polarities prepared from residues from the Brazilian pepper tree processing industry were characterized chemically by gas chromatography/mass spectrometry (GC?MS) and negative-ion mode electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI(-)FT-ICR MS). The antibacterial activity of the extracts was evaluated against multidrug-resistant strains of hospital origin (Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis, Pseudomonas aeruginosa and Acinetobacter baumannii) and standard strains (ATCC). The apolar fractions (dichloromethane and hexane) presented triterpenes as main components and the polar extracts (methanol and hydroethanolic extracts) were characterized by high contents of phenolic compounds, especially gallotannins, gallic acid and flavonoids. The methanolic fraction and the hydroethanolic extract of the residues were the most active mainly against S. aureus (MIC 0.60?0.90 mg/mL), E. faecium and E. faecalis (MIC 1.20?2.10 mg/mL). These results demonstrate the richness of bioactive compounds present in the residues and indicate a possible application of this material for the development of biotechnological products with potential against multidrug-resistant bacteria. aPepper aResidues aSchinus terebinthifolia Raddi1 aSOUZA, E. S. de1 aBARRAQUI, N. S. G.1 aTOSTA, C. L.1 aNUNES, A. P. F.1 aSCHUENCK, R. P.1 aRUAS, F. G.1 aVENTURA, J. A.1 aFILGUEIRAS, P. R.1 aKUSTER, R. M. tIndustrial Crops and Productsgv. 143, january 2020.