01446naa a2200277 a 450000100080000000500110000800800410001910000180006024501440007826000090022252006460023165000150087765000170089265300170090965300160092670000220094270000180096470000260098270000230100870000190103170000190105070000180106970000180108770000200110577300430112510237132021-09-23 2021 bl uuuu u00u1 u #d1 aSALLES, T. S. aVirucidal and antiviral activities of pomegranate (Punica granatum) extract against the mosquito-borne Mayaro virus.h[electronic resource] c2021 aThe arthropod-borne Mayaro virus (MAYV) causes ?Mayaro fever,? a disease of medical significance, primarily affecting individuals in permanent contact with forested areas in tropical South America. Recently, MAYV has attracted attention due to its likely urbanization. There are currently no licensed drugs against most mosquitotransmitted viruses. Punica granatum (pomegranate) fruits cultivated in Brazil have been subjected to phytochemical investigation for the identification and isolation of antiviral compounds. In the present study, we explored the antiviral activity of pomegranate extracts in Vero cells infected with Mayaro virus. aAlphavirus aMayaro virus aBiflavonoids aPunicalagin1 aMENESES, M. D. F.1 aCALDAS, L. A.1 aSÁ-GUIMARÃES, T. E.1 aOLIVEIRA, D. M. de1 aVENTURA, J. A.1 aAZEVEDO, R. C.1 aKUSTER, R. M.1 aSOARES, M. R.1 aFERREIRA, D. F. tParasites Vectorsgv. 14, n. 44, 2021.